In a motel room on the US/ Mexican border, a Sicario sits in a chair, his face hidden by a black veil. A Sicario is a hit man. He comes from poverty and kills for drug organizations and the government. The Sicario expects to die. But first, he seeks to recount his twenty years of kidnapping, torture and murder. This film is his confession based on the essay 'The Sicario' written by Charles Bowden published in 2009 in Harper's Magazine.